Ovarian cancer affects approximately 25,000 women every year. Although the peak age at the time of diagnosis of ovarian cancer is 57 years, 10% of women are younger than age 35 at the time of diagnosis.
The epithelial cancers, or adenocarcinomas, account for 85% of all ovarian cancers but rarely occur in women younger than age 30 years. Approximately 15% of all epithelial cancers are low malignant potential tumors, which are often found early.
The more common ovarian neoplasms in young women are the germ cell malignancies. In fact, these can occur in young children and account for more than 85% of all ovarian malignancies in girls younger than 15 years of age.
Achievement of total remission or cure is the ultimate goal of therapy. In the woman of childbearing age, consideration is given to the desire for reproductive capability, which is preserved if possible.
Treatment for ovarian cancer usually involves surgery and chemotherapy. Some women with very early stage disease may be treated with surgery alone.
This MediFocus Guide contains an extensive listing of citations and abstracts of recent journal articles that have been published about this condition in trustworthy medical journals. This is the same type of information that is available to physicians and other health care professionals. A partial selection of journal articles that are abstracted in this MediFocus Guide includes:
Current management of epithelial ovarian carcinoma: a review. Seminars in Surgical Oncology. 2000
Serous tumors of low malignant potential of the ovary. 1. Diagnostic pathology. Virchows Archiv. 2000
Ovarian mucinous cystadenocarcinoma as a cause of Zollinger-Ellison syndrome: report of a case and review of the literature. American Journal of Gastroenterology. 2000
Chemotherapy for advanced ovarian cancer. Advanced Ovarian Cancer Trialists Group. Cochrane Database of Systematic Reviews [computer file]. 2000
The genetics, screening, and treatment of epithelial ovarian cancer: an update. Cleveland Clinic Journal of Medicine. 2000
Serum markers as prognostic factors in epithelial ovarian cancer: an overview. European Journal of Gynaecological Oncology. 2000
Second-line treatment of ovarian cancer. Oncologist. 2000
Major oncogenes and tumor suppressor genes involved in epithelial ovarian cancer (review). International Journal of Oncology. 2000
Primary and salvage therapy with LH-RH analogues in ovarian cancer. Recent Results in Cancer Research. 2000
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