Uterine cancer typically involved the endometrium or inner lining of the uterus. Endometrial cancer is the most common gynecologic malignancy. Cancer may also affect the muscle of the uterus (uterine sarcoma) or the cervix (which is not discussed in this report).
Uterine cancer has the potential to spread to other areas of the body either by spreading or by cells breaking away from the original location. This is known as metastasis. Uterine cancer may spread to nearby organs such as the bladder or colon, or cells may break away and travel to the lungs, liver, or bones.
It is estimated that 37,400 women developed uterine cancer in the United States in 1999. Fortunately, most cases are diagnosed at an early stage, when surgery alone may be adequate for cure. The rate of 5-year survival for women with Stage I endometrial cancer is as high as 95%.
Surgery is the primary method of treatment for most women with uterine cancer, although additional therapies are being developed to offer options for women who wish to maintain reproductive capability. Adjuvant therapies may be needed in addition to surgery for women with advanced disease.
This MediFocus Guide contains an extensive listing of citations and abstracts of recent journal articles that have been published about this condition in trustworthy medical journals. This is the same type of information that is available to physicians and other health care professionals. A partial selection of journal articles that are abstracted in this MediFocus Guide includes:
Long-term tamoxifen treatment: a possible aetiological factor in the development of uterine carcinosarcoma: two case-reports and review of the literature. Anticancer Research. 2000
Endometrial cancer. Prevention, detection, management, and follow up. Canadian Family Physician. 2000
Problems in the differential diagnosis of endometrial hyperplasia and carcinoma. Modern Pathology. 2000
Non-Hodgkin's lymphomas involving the uterus: a clinicopathologic analysis of 26 cases. Modern Pathology. 2000
The pathology of uterine smooth muscle tumors and mixed endometrial stromal-smooth muscle tumors: a selective review with emphasis on recent advances. International Journal of Gynecological Pathology. 2000
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